Evaluation of a novel bowel cancer blood test to prioritise the colonoscopy waiting list

Phase II prospective interventional multi-site performance evaluation trial of serum Raman spectroscopy and supervised machine learning classification in a colonoscopy surveillance population

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN92139363

Enrollment

200

Registered

2026-05-20

Start date

2023-12-07

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer, high risk polyp and genetic colorectal cancer predispositions Cancer

Interventions

Patients on the surveillance colonoscopy waiting list will be invited to provide a blood sample that will be analysed by Raman spectroscopy to determine a risk score for colorectal cancer and/or advan

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Male or female patients aged over 18 years 2. Overdue colonoscopy surveillance after previous adenoma/colorectal cancer diagnosis 3. Willing to provide evidence of written informed participation 4. Willing to attend for colonoscopy

Exclusion criteria

Exclusion criteria: 1. History of invasive or haematological malignancy diagnosed within the last 3 years 2. Unwilling to participate 3. Declines colonoscopy 4. Inflammatory bowel disease surveillance

Countries

United Kingdom, Wales

Contacts

Public ContactRhodri Stacey

rhodri.stacey@wales.nhs.uk+44 (0)1792 205666

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 11, 2026