Pulmonary lung function screening (spirometry) in persons completing 6 months of treatment for active TB Infections and Infestations
Conditions
Interventions
This study involves pulmonary lung function screening (spirometry) in persons completing 6 months of treatment for active TB.
To document the prevalence of PTLD in patients enrolled at Carmelo Hospit
Sponsors
Tulane University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Primary outcome: 1. Aged =15 years of age 2. Enrolled in the National TB Control Program (NTCP) at Carmelo Hospital (CHC) with a GeneXpert-positive sputum 3. Completed six months of TB treatment and considered TB-cured 4. Ability to understand and comply with study procedures Semi-structured key-informant interviews: 1. Participants at the central level of the NTCP in Maputo (Mozambique’s capital city) 2. Administrators of CHC and at each of the three selected peripheral health facilities 3. Clinicians (physician, medical technician, and nurse) responsible for implementing the spirometry screening program at CHC, as well as all clinicians responsible for treating TB at each of the three selected peripheral health facilities
Exclusion criteria
Exclusion criteria: 1. Less than 15 years of age 2. Active respiratory symptoms at the time of screening that are indicative of a new acute respiratory illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of post-tuberculosis lung disease amongst persons completing 6 months of treatment for active TB measured using spirometry and symptom screening at baseline (completion of 6 months of TB treatment) and at 6 months after completion of TB treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Site-, provider-, and individual-level determinants that either promote or inhibit the successful adoption, implementation, and maintenance of the spirometry screening program will be measured using semi-structured key-informant interviews evaluating constructs from the Consolidated Framework for Implementation Research (CFIR), including perceptions about the intervention characteristics (e.g., facilitators, potential challenges, eligibility, and cost); outer setting factors influencing use (e.g., perception of patient needs and resources, demand creation, commitment); inner setting factors impacting uptake and fidelity to the intervention (e.g., resources needed, workload, standard operating procedures, infrastructure); characteristics of individuals (e.g., knowledge, competency, belief it can be done with quality); and process factors of implementation (e.g., fidelity, execution, and evaluation) within each health facility. These interviews will be performed after the completion of the spirometry portion of the study | — |
Countries
Mozambique
Contacts
Public ContactTroy D. Moon
Outcome results
None listed