Comparing the effectiveness of two treatments for severe cubital tunnel syndrome

Conventional ulnar nerve decompression and transposition adding supercharged end-to-side pronator quadratus motor branch to motor branch of ulnar nerve transfer vs conventional ulnar nerve decompression and transposition alone for the treatment of advanced cubital tunnel syndrome: a comparison study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN91919572

Enrollment

100

Registered

2020-07-04

Start date

2013-01-20

Completion date

Unknown

Last updated

2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced cubital tunnel syndrome Nervous System Diseases Advanced cubital tunnel syndrome

Interventions

Patients will be blinded and randomly allocated to the study group and control group. Patients in the study group will undergo the conventional ulnar nerve decompression and transposition adding super

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age >18 years 2. Severe cubital tunnel syndrome (Akahori’s Classification grade III, IV, and V) 3. A history of cubital tunnel syndrome >6 months 4. Unilateral limb involvement 5. Atrophy of intrinsic hand muscles innervated by the ulnar nerve, which was defined as a sign of advanced disease, no matter manifestation of grip weakness 6. A conduction velocity of 40 m/s or greater 7. No improvement or worse symptoms in mild disease after 3 months of nonsurgical treatments

Exclusion criteria

Exclusion criteria: 1. An additional lesion, such as cervical neuropathy 2. Thoracic outlet syndrome, or Guyon’s canal syndrome 3. Deformity or distortion of the cubital tunnel 4. Associated medical conditions capable of causing a non-compressive neuropathy, such as diabetes mellitus and rheumatism 5. Revision surgery for cubital tunnel syndrome

Design outcomes

Primary

Measure	Time frame
Grip strength using a Jamar dynamometer (Sammons Preston Rolyan, Bolingbrook, Illinois), key pinch strength using a pinch gauge (B&L Engineering, Santa Ana, California), and tripod pinch strength (Baseline Hydraulic Pinch Meter, Fabrication Enterprises Inc., Irvington, NY, USA) at baseline and two years	—

Secondary

Measure	Time frame
1. 2-point discrimination of the little finger measured using Disk-Criminator (MackinnonDellon Partnership, Baltimore, MD) at baseline and two years 2. Disabilities of the Arm, Shoulder, and Hand measured using Gabel/Amadio score and disabilities of the arm, shoulder, and hand (DASH) questionnaire at baseline and two years	—

Countries

China

Contacts

Public ContactQing Xie

qxie710@sina.com+86-13273148710

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026