Mucosa membrane dryness Urological and Genital Diseases Menopausal and other perimenopausal disorders
Conditions
Interventions
Group one: omega 7 capsules 2 x 2 capsules per day for 4 months
Group two: placebo capsules (medium chain triglycerides), 2 x 2 capsules per day for 4 months
Sponsors
Turku University Central Hospital (Finland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy post-menopausal females aged 55 - 70 years 2. Dryness, itching, pain, burning and/or inflammation in the mucosa of the genital tract 3. Problem of the genital tract mucosa shall not have clear association with severe diseases
Exclusion criteria
Exclusion criteria: 1. Severe diseases and/or receiving systematic medications such as hormone replacement therapy, anti-inflammatory and cholesterol lowering drugs 2. Diabetes 3. Hormonal, renal, haematological, or hepatic dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Dryness, itching, pain, burning and/or inflammation in the mucosa of the genital tract at baseline, after one and four months of supplementation 2. Vaginal PH at baseline, after one and four months of supplementation 3. Maturation index of vaginal mucosa at baseline, after one and four months of supplementation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Plasma total anoxidative capacity at baseline, after one and four months of supplementation 2. Plasma isoprostane level at baseline, after one and four months of supplementation 3. Plasma C-reactive protein level at baseline, after one and four months of supplementation | — |
Countries
Finland
Outcome results
None listed