Identify and understand patient-ventilator asynchrony in patients with mechanical ventilation using electrical impedance tomography

Identification and mechanism of patient-ventilator asynchrony (PVA) in patients with mechanical ventilation by electrical impedance tomography (EIT)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN91644265

Enrollment

Registered

2021-08-25

Start date

2021-08-01

Completion date

Unknown

Last updated

2021-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring invasive mechanical ventilation Respiratory

Interventions

After the eligible patients are enrolled, we will use the respcare information system continuously and automatically collect the ventilator waveform and record the respiratory mechanical parameters. W

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients admitted to ICU from August 2021 to December 2022 2. Age =18 years old 3. Patients with mechanical ventilation 4. Voluntarily participate and sign the informed consent form (in case of incapacity, its legal representative must sign the informed consent on behalf of it)

Exclusion criteria

Exclusion criteria: 1. Signed the doctor's order against resuscitation (DNR) 2. Patients transferred from other intensive care units 3. No effective mechanical ventilation waveform 4. Unable to conduct EIT assessment

Design outcomes

Primary

Measure	Time frame
Current primary outcome measures as of 31/08/2021: 1. Esophageal internal pressure (4 times a day, 1 hour each time) measured using the ventilator 2. To assess the accuracy of EIT in identifying PVA, the gas distribution in the lung was observed by chest wall electrical impedance imaging (4 times a day, 1 hour each time). By comparing the impedance change with the reference state, the improved Newton Raphson algorithm was used to reconstruct the tidal volume distribution image. 3. Incidence and type of PVA were recorded throughout the duration of mechanical ventilation _____ Previous primary outcome measures: 1. Esophageal internal pressure (4 times a day, 1 hour each time) measured using the ventilator 2. The gas distribution in the lung was observed by chest wall electrical impedance imaging (4 times a day, 1 hour each time): by comparing the impedance change with the reference state, the improved Newton Raphson algorithm was used to reconstruct the tidal volume distribution image. 3. Incidence and type of PVA were recorded throughout the duration of mechanical ventilation	—

Measure

Time frame

Current primary outcome measures as of 31/08/2021: 1. Esophageal internal pressure (4 times a day, 1 hour each time) measured using the ventilator 2. To assess the accuracy of EIT in identifying PVA, the gas distribution in the lung was observed by chest wall electrical impedance imaging (4 times a day, 1 hour each time). By comparing the impedance change with the reference state, the improved Newton Raphson algorithm was used to reconstruct the tidal volume distribution image. 3. Incidence and type of PVA were recorded throughout the duration of mechanical ventilation _____ Previous primary outcome measures: 1. Esophageal internal pressure (4 times a day, 1 hour each time) measured using the ventilator 2. The gas distribution in the lung was observed by chest wall electrical impedance imaging (4 times a day, 1 hour each time): by comparing the impedance change with the reference state, the improved Newton Raphson algorithm was used to reconstruct the tidal volume distribution image. 3. Incidence and type of PVA were recorded throughout the duration of mechanical ventilation

—

Secondary

Measure	Time frame
Current primary outcome measures as of 31/08/2021: 1. As continuous assessment of respiratory physiological aspects and mechanics of different subtypes, the Respcare information system continuously and automatically collects the ventilator waveform and records the respiratory mechanical parameters throughout the duration of mechanical ventilation: PES, Pplat, flow and volume 2. Length of stay and mortality were recorded at the end of mechanical ventilation _____ Previous secondary outcome measures: 1. The Respcare information system continuously and automatically collects the ventilator waveform and records the respiratory mechanical parameters throughout the duration of mechanical ventilation: PES, Pplat, flow and volume. 2. Length of stay and mortality were recorded at the end of mechanical ventilation	—

Measure

Time frame

Current primary outcome measures as of 31/08/2021: 1. As continuous assessment of respiratory physiological aspects and mechanics of different subtypes, the Respcare information system continuously and automatically collects the ventilator waveform and records the respiratory mechanical parameters throughout the duration of mechanical ventilation: PES, Pplat, flow and volume 2. Length of stay and mortality were recorded at the end of mechanical ventilation _____ Previous secondary outcome measures: 1. The Respcare information system continuously and automatically collects the ventilator waveform and records the respiratory mechanical parameters throughout the duration of mechanical ventilation: PES, Pplat, flow and volume. 2. Length of stay and mortality were recorded at the end of mechanical ventilation

—

Countries

China

Contacts

Public ContactJIE DING

2233702918@qq.com+86 18268113280

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026