Cold versus hot snare polypectomy in post polypectomy bleeding in small colonic polyps

A prospective, randomised comparison of cold versus hot snare polypectomy in the occurrence of post polypectomy bleeding in small colonic polyps

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN91553378

Enrollment

414

Registered

2011-05-06

Start date

2010-05-19

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic polyps Digestive System Colonic polyps

Interventions

Colonoscopic polypectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All patients founded with small polyps (3 - 8 mm) during colonoscopy 2. Cold snare group (CSP): male/female: 107/101 with age range: 59,4±13,6 3. Hot snare group (HSP): male/female: 125/81 with age range: 61,3±11,0

Exclusion criteria

Exclusion criteria: 1. Cases with bleeding tendency (taking anticoagulant therapy, platelet count of less than 100,000/mm3, or prothrombin time more than 30% above the control 2. Cases with inadequate colonic preparation 3. Patients undergoing anticoagulant or antiplatelet therapy were instructed to discontinue the use of these types of medication at least 7 days before the endoscopic procedure

Design outcomes

Primary

Measure	Time frame
1. Post polypectomy bleeding 2. All patients were contacted by telephone 12 hours, 2 days and 1 month after procedure and were asked about pain, abdominal tenderness, fever and bleeding 3. In the HSP group, small polyps were removed as a single piece with a standard electrosurgical snare (Sensation Polypectomy Snare 13mm, Microvasive, Boston Scientific, Natick, MA) and monopolar coagulation current, using a 120W OLYMPUS HF-120 generator with a setting of 72W in ?endocut? function 4. In the CSP group, the polyp was removed as a single piece with the same electrosurgical snare. According to expert opinion[3] 1-to 2mm of normal tissue around the small polyp were ensnared in the CSP group. All colonoscopies were performed with wide-angle (170o), high-resolution videocolonoscopes ? Olympus (CFH180AL, Tokyo, Japan) with a high-definition 1080-line screen - Olympus (OEV191H, Tokyo, Japan) and video processor Olympus (EVIS EXERA II CV-180, Tokyo, Japan). 5. Bowel preparation was accomplished with a 4L electrolyte solution of polyethylene glycol.	—

Measure

Time frame

1. Post polypectomy bleeding 2. All patients were contacted by telephone 12 hours, 2 days and 1 month after procedure and were asked about pain, abdominal tenderness, fever and bleeding 3. In the HSP group, small polyps were removed as a single piece with a standard electrosurgical snare (Sensation Polypectomy Snare 13mm, Microvasive, Boston Scientific, Natick, MA) and monopolar coagulation current, using a 120W OLYMPUS HF-120 generator with a setting of 72W in ?endocut? function 4. In the CSP group, the polyp was removed as a single piece with the same electrosurgical snare. According to expert opinion[3] 1-to 2mm of normal tissue around the small polyp were ensnared in the CSP group. All colonoscopies were performed with wide-angle (170o), high-resolution videocolonoscopes ? Olympus (CFH180AL, Tokyo, Japan) with a high-definition 1080-line screen - Olympus (OEV191H, Tokyo, Japan) and video processor Olympus (EVIS EXERA II CV-180, Tokyo, Japan). 5. Bowel preparation was accomplished with a 4L electrolyte solution of polyethylene glycol.

—

Secondary

Measure	Time frame
All patients were contacted by telephone 12 hours, 2 days and 1 month after procedure and were asked about: 1. Pain 2. Abdominal tenderness 3. Fever 4. Bleeding	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026