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Investigating the impact of the coronavirus (COVID-19) pandemic on children presenting to emergency departments across Europe

The epidemiology, severity, and outcomes of children presenting to emergency departments across Europe during the SARS-COV-2 pandemic: the EPISODES study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN91495258
Enrollment
2400000
Registered
2020-07-14
Start date
2018-01-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatric emergency department presentation Not Applicable Paediatric emergency department presentation, impact of COVID-19 (SARS-CoV-2 infection)

Interventions

Current interventions as of 01/04/2021: This study will involve retrospective analysis of routinely collected clinical data of all children presenting to emergency departments across Europe over a 2 a

Sponsors

Imperial College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All children presenting to the emergency department during the period of interest for unscheduled health care 2. Aged between 0 and 18 years (upper age limit determined by the upper age bracket for children being assessed at the local participating centre) 3. Undergo a formal clinical assessment by advanced nurse practitioner (or equivalent) or clinician in the emergency department 4. All or part of the data of the triaging process (including vital signs), consultation, management (including diagnostics and treatment) and outcomes (including working diagnosis and disposition) routinely documented in the electronic patient record

Exclusion criteria

Exclusion criteria: 1. Children visiting the emergency department who are then streamed to a primary care service for the initial consultation. 2. Children presenting to the emergency department for scheduled health care or a planned follow-up visit (children who have an unscheduled re-visit to the emergency department within one disease episode are not excluded)

Design outcomes

Primary

MeasureTime frame
Absolute numbers of children presenting to the paediatric emergency department over the period of interest; for all children and children with different typologies (i.e. working diagnosis, age)

Secondary

MeasureTime frame
1. The severity of illness of children presenting to the paediatric emergency department over the period of interest as defined by the following criteria: percentage of children with abnormal vital parameters; high triage urgency; a composite outcome of the need for emergency medications, the need for hospital admission for >24 h, the need for PICU admission, and death 2. Change of relative incidence of children with specific diagnoses of interest and the severity of their presentation as a proxy for timeliness of presentations. Calculated from: absolute numbers of children presenting to the paediatric emergency department; the percentage of children with abnormal vital parameters; the number of cases with high triage urgency; a composite outcome of the need for emergency medications, the need for hospital admission for >24 h, the need for PICU admission, and death; over the period of interest and over an equivalent historical time period for comparison

Countries

Austria, England, France, Germany, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Malta, Netherlands, Portugal, Slovenia, Spain, Sweden, Türkiye, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 15, 2026