A randomised study comparing three types of vein harvesting method for coronary artery bypass surgery

A randomised study comparing Vein Integrity and Clinical Outcomes (VICO) in open vein harvesting and two types of endoscopic vein harvesting for Coronary Artery Bypass Surgery - The VICO trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN91485426

Enrollment

450

Registered

2014-09-18

Start date

2011-01-01

Completion date

Unknown

Last updated

2017-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery bypass surgery Surgery

Interventions

Computer block randomisation assigned the patients to undergo an open vein harvesting (control group: n=150), Closed tunnel CO2 endoscopic vein harvesting (n=150) and Open tunnel CO2 endoscopic vein h

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing CABG surgery at the University Hospital of South Manchester 2. Aged 18 or over 3. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Any patient who refuses or withdraws the consent 2. Patients undergoing emergency surgery or a contra-indication to a technique including varicose vein on the long saphenous vein, small or thin legs and a superficial LSV

Design outcomes

Primary

Measure	Time frame
Long saphenous vein integrity, as indicated by the level of histological damage	—

Secondary

Measure	Time frame
1. Post-surgical clinical outcomes, specifically major adverse cardiac events such as reoccurrence of angina, myocardial infarction, vein graft failure, mortality and wound complications 2. Patient reported outcomes: generic health related quality of life 3. Health economic analysis: the costs and effects of the three approaches to vein harvesting	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026