Colorectal cancer Cancer Colorectal
Conditions
Interventions
Following surgery patients are randomised to one of two treatment arms:
1. Arm A: Post-operative radiotherapy, a midplane dose of 45 Gy given over 4 to 5 weeks
2. Arm B: No radiotherapy
Sponsors
Northern and Yorkshire Clinical Trials and Research Unit (UK)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Histologically proven adenocarcinoma of the rectum 2. Surgery at or below pelvic brim 3. Curative operation, all macroscopic disease removed 4. Aged <80 years, 75 years if physically unfit 5. No previous history of multiple abdominal or pelvic surgical procedures 6. No evidence of small bowel descending into area of maximum dose of radiotherapy 7. Adequate bone marrow function
Exclusion criteria
Exclusion criteria: Not provided at time of registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed