Limited skin areas and vitamin D

An experimental photodermatology study to examine the ability of limited skin areas to produce vitamin D

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN91255549

Enrollment

Registered

2015-02-04

Start date

2014-11-01

Completion date

Unknown

Last updated

2015-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Dermatology

Interventions

The intervention is solar-simulated ultraviolet radiation. A dose of 1.3 SED (standard erythema dose) is given three times a week for 6 weeks. There is no control arm. Blood samples are taken at the s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy, ambulant, male and female adults aged 20-60 years 2. White Caucasian (sun-reactive skin type I-IV) 3. Willing and capable of participating to the extent and degree required by the protocol

Exclusion criteria

Exclusion criteria: 1. Sunbathing or sunbed use in the last 3 months 2. Taking photoactive medication 3. Taking vitamin D, fish oil or calcium supplements 4. History of skin cancer or photosensitivity disorder 5. Pregnancy/lactation

Design outcomes

Primary

Measure	Time frame
The primary outcome measure is serum 25-hydroxyvitamin D (25(OH)D) concentration which is measured at baseline, then weekly up to 6 weeks. Further samples to be taken at weeks 8, 10 and 12. Serum 25(OH)D is measured by liquid chromatography tandem mass spectrophotometry (LC-MS/MS).	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026