Healing of apical periodontitis (due to primary endodontic infection) Oral Health
Conditions
Interventions
Patients with root canal disease (also known as pathology of endodontic origin) who meet the inclusion criteria and not the exclusion criteria will be randomly allocated to one of three groups. The en
Sponsors
University of Central Lancashire
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients either male or female over the age of 18 (who can consent for themselves) in good general health 2. Patients with clinical symptoms of pathology of endodontic origin who need endodontic treatment 3. All anterior and posterior teeth included in study
Exclusion criteria
Exclusion criteria: 1. External or internal root resorption 2. Pregnant women, in view of requirements for radiographs. 3. Patients younger than 18 years. 4. Patients unable to give consent. 5. Patients who have been administered antibiotics in the previous month. 6. Immunocompromised patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing outcome after non-surgical treatment measured using clinical examination (intact restoration, no fistulas or swelling, no mobility of the teeth or tenderness to percussion) and radiographical assessment using periapical radiographs and CBCT (absence or reduction of any radiolucencies or widening of the periodontal ligament space and vertical or horizontal fractures and absence of external root resorption) at 12 months and 24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Patient self-reported pain measured using VAS (Visual Analogue Scale) pre-operatively, and then day 1, 3, 5, 7 and 14 following the treatment 2. Patients' quality of life measured using OHIP-14 preoperatively and at year 1 and year 2 | — |
Countries
England, United Kingdom
Contacts
Public ContactShalini;Tiago Kanagasingam;Pimentel
;
Outcome results
None listed