Dry skin and/or eczema Skin and Connective Tissue Diseases
Conditions
Interventions
All patients with dry skin and/or eczema in 2008 and 2012 will be identified. Of those, patients with at least 2 distinct emollient prescriptions within 6 months of index will be identified and includ
Sponsors
Johnson & Johnson Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with dry skin and/or eczema in 2008 and 2012 2. Exposed cohort: patients with at least 2 distinct emollient prescriptions within 6 months of index 3. Control cohort: patients with 2 healthcare exposures (visits or prescriptions) for dry skin and/or eczema in 6 months but no emollient prescriptions at any time 4. Continuous = 12 months of medical history prior to diagnosis (washout period) and = 24 months post dry skin and/or eczema diagnosis. The index date will be the date of dry skin and/or eczema diagnosis in those patients with at least 12 months washout period (i.e., first diagnosis in at least 12 months – this constitutes the “clean” period)
Exclusion criteria
Exclusion criteria: 1. Patients with concurrent skin diseases that are typically treated with topical corticosteroids (TCS) such as bullous pemphigoid, lupus, lichen planus, granuloma annulare, lichen sclerosis, alopecia areata and vitiligo 2. Patients with low-quality records or non-continuous data coverage 3. A diagnosis of dry skin-eczema during the washout period (12 months period prior to index diagnosis)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Measured using CPRD database over a two year period from initial diagnosis (post-index): 1. Percentage of patients treated with potent or very potent topical corticosteroids 2. Percentage of patients treated with antimicrobials and/or antibiotics | — |
Primary
| Measure | Time frame |
|---|---|
| Measured using CPRD database over a two year period from initial diagnosis (post-index): 1. Health care utilisation: 1.1 Frequency of GP visits 1.2. Prescriptions for dry skin and eczema | — |
Countries
United Kingdom
Outcome results
None listed