Enhancement of recovery following hip fracture surgery Musculoskeletal Diseases
Conditions
Interventions
Pre-op carbohydrate drink, Nutricia Pre-op(r)
400 ml night before surgery
400 ml morning of surgery (up to 2 hours pre-op)
Follow Up Length: 1 month(s)
Sponsors
University of Nottingham (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients presenting through accident and emergency with a fragility neck of femur fracture requiring hemiarthroplasty 2. Aged 70 or over 3. Patients able to provide fully informed consent
Exclusion criteria
Exclusion criteria: 1. Patients who are confused or unable to give their own consent 2. Patient known to suffer with diabetes (either type 1 or type 2) 3. Patients with current infections 4. Ongoing participation in another clinical trial 5. Multiple injuries requiring operative management 6. Previous intolerance to carbohydrate drinks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral glucose tolerance test; Timepoint(s): Day 1 post operation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Glucose homeostasis - blood glucose; Timepoint(s): Blood glucose prior to induction of anaesthesia 2. Blood glucose on day 1; Glucose homeostasis - insulin; Timepoint(s): Insulin concentration - prior to induction of anaesthesia, Insulin concentration - day 1 post op 3. Length of acute hospital stay; Timepoint(s): Hospital discharge 4. Mobility - Cumulated ambulation score; Timepoint(s): Days 1-3 post-op 5. Muscle metabolism - muscle biopsy, contralateral leg; Timepoint(s): Prior to induction of anaesthesia At end of surgery Day 1 6. Nausea and vomiting; Timepoint(s): Prior to induction of anaesthesia Day 1 post-operation | — |
Countries
United Kingdom
Outcome results
None listed