Obesity Nutritional, Metabolic, Endocrine Obesity
Conditions
Interventions
Participants are randomised to one of two groups using an online random number generator. Those in the first group (N=8) complete 6 sessions of HIIT exercise over a 2-week period where as group 2 (N=1
Sponsors
Loughborough University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. BMI = 27 kg·m-2 2. Reported taking part in any form of exercise less than 2 times per week 3. Otherwise healthy 4. Male
Exclusion criteria
Exclusion criteria: 1. Smokers 2. Previously diagnosed with impaired fasting glucose or diabetes 3. BMI = 40 kg.m-2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting glucose is measured via an oral glucose tolerance test (OGTT) which will be performed one week prior to intervention and 72 hours immediately post the last exercise session in week two. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory profile is assessed at baseline, 1 week prior to intervention and once again 72 hours post-the final exercise bout. Inflammatory profile is assessed by measuring: 1. Adiponectin, MCP-1 and CRP using commercial sandwich enzyme linked immunosorbent assays (ELISAs) 2. CRP and TNF-avia using high sensitivity ELISAs (R & D systems, Minneapolis, MN, USA) 3. Plasma IL-6 and sIL-6R via ‘in-house’ ELISAs | — |
Countries
United Kingdom
Outcome results
None listed