Screening for lung cancer by chest radiography

Screening for lung cancer by chest radiography: a non-randomised cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN90639073

Enrollment

7000

Registered

2011-12-21

Start date

1997-07-01

Completion date

Unknown

Last updated

2017-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer Cancer Malignant neoplasm of bronchus and lung

Interventions

1. Baseline CXR screening and annual repeat screen for 4 years, in addition to usual care 2. Smoking cessation advice

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects of both genders 2. 45-75 years of age 3. Cigarette smoking history of >10 pack-years (current smoker or ex-smoker for less than 10 years) 4. Resident in Italy 5. Do not have symptoms of lung cancer: 5.1. Bloody or worsening cough 5.2. Hoarseness 5.3. Unexplained weight loss 6. Not diagnosed with or suspected of having lung cancer

Exclusion criteria

Exclusion criteria: 1. Moderate or poor health 2. Unfit for possible thoracotomy

Design outcomes

Primary

Measure	Time frame
Lung cancer specific mortality (reduction)	—

Secondary

Measure	Time frame
1. Lung cancer detection results: 1.1. Lung cancer stage distribution 1.2. Histological subtype distribution 1.3. Resectability 2. Overall survival and lung-cancer specific survival 3. Cost-effectiveness	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026