Utility of visual inspection of the cervix in diagnosing early forms of cervical CANcer in HIV positive women

Effect of HIV infection on Human Papilloma Virus (HPV) distribution pattern, cervical cancer burden and diagnostic accuracy of direct visual inspection in Nigeria

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN90623294

Enrollment

1000

Registered

2013-01-17

Start date

2011-12-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV, premalignant lesion of the cervix Cancer Malignant neoplasm of cervix uteri

Interventions

Screening of premalignant conditions of the cervix using visual inspection with Direct Visual Inspection (DVI) with Acetic acid (DVIA) and/or Lugol's Iodine (DVILI).

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Nigerian 2. Female 3. Aged 18 years or over 4. Known HIV status

Exclusion criteria

Exclusion criteria: 1. Known reaction to Lugol's iodine 2. Refusal to do HIV test 3. Overt cancer of the cervix

Design outcomes

Primary

Measure	Time frame
Premalignant lesion of the cervix	—

Secondary

Measure	Time frame
High-risk HPV types	—

Countries

Nigeria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026