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Vitamin D levels in chronic kidney disease (CKD)

Vitamin D in children with chronic kidney disease (CKD) on dialysis: a non-randomised interventional treatment pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN90413758
Enrollment
30
Registered
2010-04-29
Start date
2009-01-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Medicines for Children Research Network

Interventions

Baseline 1,25(OH)2D levels will be measured. The alfacalcidol dose will be adjusted so as to keep the serum 1,25(OH)2D level in the normal range (40 ? 150 pmol/L). Levels will be checked every 4 weeks

Sponsors

Great Ormond Street Hospital for Children (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 30 children aged 5 to 18 years, either sex 2. CKD stage 5 (estimated glomerular filtration rate [GFR] less than 15 ml/min/1.73 m^2 or on dialysis)

Exclusion criteria

Exclusion criteria: 1. Smokers 2. Diabetics 3. Uncontrolled hypertension 4. Inflammatory disorders 5. Receiving anti-epileptic medications 6. Liver disease

Design outcomes

Primary

MeasureTime frame
Blood samples taken at 4 weeks

Secondary

MeasureTime frame
Scans annually or prior to transplant

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026