Cardiovascular rehabilitation adapted to transient ischaemic attack and stroke

A randomised controlled trial to evaluate the benefit of a cardiac rehabilitation programme for improving fitness and reducing cardiovascular risk factors in the non-acute ischaemic stroke and transient ischaemic attack populations

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN90272638

Enrollment

240

Registered

2008-09-29

Start date

2007-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, transient ischaemic attack Circulatory System Transient cerebral ischaemic attacks and related syndromes

Interventions

Over 8 weeks: Control subjects will attend two one-hour educational session addressing risk factor reduction and lifeskills. Intervention subjects will attend the two educational classes listed above

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults of either gender aged greater than 18 years of age who have sustained an ischaemic stroke (confirmed by computed tomography [CT] or magnetic resonance imaging [MRI]) or a transient ischaemic attack (TIA) 2. Cerebrovascular accident [CVA] greater than one year recruited through the community with medical consent 3. CVA less than 1 year with consent of their hospital consultant 4. TIA greater than 3 months with consent of their hospital consultant

Exclusion criteria

Exclusion criteria: 1. Major medical conditions 2. Oxygen dependence 3. Unstable cardiac conditions including angina 4. Uncontrolled diabetes 5. Claudication 6. Acute febrile illness 7. Cognitive impairment 8. Pregnancy 9. Uncontrolled diabetes

Design outcomes

Primary

Measure	Time frame
1. Adherence to the European guidelines for cardiovascular disease prevention in a high risk group as evidenced by the % of smokers, fruit and vegetable intake and habitual exercise, i.e. % taking moderate to vigorous activity greater than three times a week extrapolated from the International Physical Activity Questionnaire 2. Cardiac Risk Score Baseline measures of the primary and secondary outcomes will be taken on week 1. Reassessment will be conducted on week 10 and at a one year interval.	—

Measure

Time frame

1. Adherence to the European guidelines for cardiovascular disease prevention in a high risk group as evidenced by the % of smokers, fruit and vegetable intake and habitual exercise, i.e. % taking moderate to vigorous activity greater than three times a week extrapolated from the International Physical Activity Questionnaire 2. Cardiac Risk Score Baseline measures of the primary and secondary outcomes will be taken on week 1. Reassessment will be conducted on week 10 and at a one year interval.

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Secondary

Measure	Time frame
1. Physical fitness: VO2 as calculated from a steady state sub-maximal cycle ergometry test 2. Health related quality of life as measured by the Stroke Specific Quality of Life Index, Hospital Anxiety and Depression Scale, Functional Health Status COOP/WONCA Scale 3. Economic evaluation derived from EuroQol-5D Baseline measures of the primary and secondary outcomes will be taken on week 1. Reassessment will be conducted on week 10 and at a one year interval.	—

Measure

Time frame

1. Physical fitness: VO2 as calculated from a steady state sub-maximal cycle ergometry test 2. Health related quality of life as measured by the Stroke Specific Quality of Life Index, Hospital Anxiety and Depression Scale, Functional Health Status COOP/WONCA Scale 3. Economic evaluation derived from EuroQol-5D Baseline measures of the primary and secondary outcomes will be taken on week 1. Reassessment will be conducted on week 10 and at a one year interval.

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Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026