Soil-transmitted helminthiasis (ascariasis, hookworm disease, trichuriasis) Infections and Infestations Ascariasis
Conditions
Interventions
Each day, a total of 20 children will be enrolled. They are invited to provide a single stool sample that will be subjected to three different diagnostic methods. After stool collection, each child wi
each child will be administered albendazole (400 mg).
Sponsors
Ivo de Carneri Foundation (Italy)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Child judged healthy by study physician 2. Written informed consent provided by child's parent or guardian 3. Provision of stool sample 4. No recent history of anthelminthic treatment (drugs administered within the past 2 weeks) 5. School-aged children between 5 and 16 years (although in some cases this can go as high as 20 years), either sex
Exclusion criteria
Exclusion criteria: 1. Too sick to attend school or participate in the study (e.g. severe diarrhoea, severe anaemia, high fever, etc.) 2. No parental/guardian's permission to participate (absence of written informed consent) 3. Do not provide a stool sample 4. Recent history of anthelminthic treatment (drugs administered within the past 2 weeks)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Measured at three weeks post-treatment follow-up: 1. Agreement between diagnostic tests for prevalence and infection intensity estimates 2. Negative predictive value | — |
Primary
| Measure | Time frame |
|---|---|
| Sensitivity of diagnost test, measured at three weeks post-treatment follow-up | — |
Countries
Tanzania
Outcome results
None listed