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Bacteraemia post-urological instrumentation: endocarditis risk?

A one-year, prospective, observational, cohort, single centre study on the incidence, intensity, duration and identity of bacteraemia in patients undergoing transurethral resection of the prostate (TURP), extracorporeal shockwave lithotripsy (ESWL) and urinary catheter change

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN89902973
Enrollment
750
Registered
2009-12-08
Start date
2009-12-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacteraemia Infections and Infestations Bacterial infection of unspecified site

Interventions

The enrolled participants will provide a urine sample prior to the start of their procedure. They will then have an intravenous cannula inserted aseptically, preferably in their antecubital fossa. Th

Sponsors

Leeds Teaching Hospitals NHS Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adults (18 years onwards) 2. Both male and female (male only for the transurethral resection of the prostate [TURP] cohort) 3. Patient undergoing TURP, extracorporeal shock-wave lithotripsy and urinary catheter change at the Leeds Teaching Hospital NHS Trust

Exclusion criteria

Exclusion criteria: 1. Age less than 18 years 2. Not competent to consent for enrolment in the study 3. Signs and symptoms of ongoing infection (of any source) at presentation to the hospital 4. Use of systemic antibiotics within the 2 weeks of presentation to the hospital 5. Recent (within 2 weeks) instrumentation of the urological tract (not including urethral or suprapubic catheterisation) 6. Patient with poor veins, leading to difficult venous cannulation

Design outcomes

Primary

MeasureTime frame
Presence of bacteraemia, assessed at time of culture and PCR

Secondary

MeasureTime frame
Development of infective endocarditis. A year after obtaining the samples, participants will be contacted by phone or mail to see whether they have suffered an episode of infection in that year which required hospital admission. If that is the case, the hospital notes of the said patients will be obtained and data collected from the notes about the said episode of infection.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026