Effect of calcium supplementation on iron bioavailability in women aged 35 to 45 years old

A randomized controlled trial investigating the effect of calcium supplementation on iron bioavailability in women aged 35 to 45 years old in Santiago, Chile

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN89888123

Enrollment

Registered

2011-07-13

Start date

2011-06-15

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iron bioavailability, iron-calcium interaction Nutritional, Metabolic, Endocrine Iron deficiency

Interventions

The target sample will consist of pre-menopausal women aged 35 to 45 years old, from the South East Area of Santiago Metropolitan Area, Chile. A group of 14 subjects supplemented with 600 mg of carbon

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Apparently healthy women 2. Thirty five to 45 years old 3. Not participating in other clinical studies 4. Contraceptive use

Exclusion criteria

Exclusion criteria: 1. Morbidity (excepting anemia defined as hemoglobin < 120 g/L) 2. Daily use of medicaments 3. Pregnancy and pregnant interest (including a pregnancy test before the start of the study) 4. Breastfeeding 5. Iron and/or calcium supplementation 6. Postmenopausal women 7. Participation in previous studies particularly involving the administration of radioactive labeled iron 8. Smoking

Design outcomes

Secondary

Measure	Time frame
1. Iron status 1.1. Hemoglobin 1.2. Mean corpuscular volume 1.3. Zn protoporphyrin 1.4. Serum ferritin 1.5. Total iron binding capacity 1.6. Serum Iron 1.7. Hepcidin 1.8. Transferrin Receptor 1.9. Transferrin Saturation 1.10. Total body iron 2. Nutritional state by anthropometry 3. Dietary calcium and iron daily intake	—

Primary

Measure	Time frame
1. Heme iron bioavailability 2. Non heme iron bioavailability	—

Countries

Chile

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026