A study of a new technique for organ preservation

A non-randomised controlled pilot study of normothermic regional perfusion in organ donors following cardiac death

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN89667087

Enrollment

Registered

2009-10-07

Start date

2009-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Organ transplantation Surgery Transplanted organ and tissue status

Interventions

Control arm: cannulae will be placed in the aorta and vena cava and cold Soltran™ preservation solution perfused through the abdominal organs, following which they will be removed. Duration: 30 to 60

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Individuals dying on an intensive care unit diagnosed by cardiac criteria and becoming solid organ donors 2. Deceased donors: aged 18 to 70 years, either sex; Recipients: aged 18 to 75 years, either sex

Exclusion criteria

Exclusion criteria: Time from withdrawal of treatment to death over 2 hours

Design outcomes

Primary

Measure	Time frame
Number of potential organs used for transplantation	—

Secondary

Measure	Time frame
Measured at 3 months: 1. Measures of function in the first week post-transplantation 2. Graft and patient survival for liver, kidney and pancreas	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026