Skip to content

Effects of tramadol and dexmedetomidine on recovery in pediatric patients undergoing adenotonsillectomy

Tramadol vs dexmedetomidine for emergence reaction control in pediatric patients undergoing adenotonsillectomy with sevoflurane anesthesia: Prospective randomised controlled clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN89326952
Enrollment
80
Registered
2016-07-25
Start date
2013-01-01
Completion date
Unknown
Last updated
2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after adenotonsillectomy Signs and Symptoms Postoperative pain after adenotonsillectomy

Interventions

Patients are randomised to one of two groups according to a computer generated random numbers table. Group 1: After intubation, patients receive 1 µg/kg dexmedetomidine diluted in sal

Sponsors

Gazi university, Medical Faculty
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients ASA physical status I-II 2. Aged between 2 and 12 3. Undergoing adenotonsillectomy

Exclusion criteria

Exclusion criteria: 1. Developmental delay 2. Cardiac disorder 3. Psychological disorder 3. Epilepsy 4. Allergy to study medications

Design outcomes

Primary

MeasureTime frame
Pain intensity is assessed using a modified Hannallah pain score and observational pain score (OPS), pediatric anesthesia emergence delirium (PAED) scale, Ramsay sedation score (RSS) on arrival to PACU and 5, 10, 15, 30, 45, 60 minutes after arrival to PACU.

Secondary

MeasureTime frame
1. Heart rate is measured before induction (baseline), at induction and every 5 minutes after induction during the procedure 2. Mean arterial pressure is meaured before induction (baseline), at induction and every 5 minutes after induction during the procedure 3. Adverse events are monitored through clinical observations on arrival to PACU and 5, 10, 15, 30, 45, 60 minutes after arrival to PACU

Countries

Turkey

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 10, 2026