Pharmacologic versus Optical Penalisation in the treatment of Amblyopia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN89210627

Enrollment

Registered

2007-10-10

Start date

2007-11-01

Completion date

Unknown

Last updated

2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amblyopia Eye Diseases Amblyopia

Interventions

70 children 2 to 10 years of age are randomised to atropine or optical penalisation for the treatment of amblyopia. 1% atropine (Colircusi Atropina 1%, AlconCusi, Barcelona, Spain) wi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 2 - 10 years 2. Ability to cooperate with measurement of visual acuity by the logarithmic Minimal Angle Resolution (logMAR) crowded test with at least 2 logMAR lines of difference in visual acuity between the two eyes

Exclusion criteria

Exclusion criteria: 1. Previous amblyopia treatment 2. Previous eye surgery 3. Ocular disease

Design outcomes

Primary

Measure	Time frame
Lines of improvement of visual acuity of the amblyopic eye at 6 months.	—

Secondary

Measure	Time frame
Stereoacuity measurement at 6 months.	—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026