A randomised controlled study of Epidural Fentanyl Analgesia following Lumbar Laminectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN89059431

Enrollment

100

Registered

2007-02-28

Start date

2006-12-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative lumbar canal stenosis Musculoskeletal Diseases Dorsopathies

Interventions

Single bolus intraoperative epidural fentanyl (100 micrograms) versus best alternative medical care in patients following lumbar laminectomy.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Having a lumbar laminectomy for degenerative canal stenosis 2. 18 years or older 3. Able to give informed consent for this trial

Exclusion criteria

Exclusion criteria: 1. There is a Cerebrospinal Fluid (CSF) leak or the dura is opened 2. Contraindication to fentanyl as follows: a. respiratory depression b. obstructive airways disease c. concurrent administration with monoamine oxidase inhibitors, or within two weeks of their discontinuation d. known intolerance to fentanyl 3. Vulnerable group or unable to consent

Design outcomes

Primary

Measure	Time frame
Post-operative pain score, day one and day two.	—

Secondary

Measure	Time frame
1. Length of post-operative hospital stay 2. Post-operative analgesia requirements 3. Side effects: a. urinary retention b. nausea c. vomiting d. pruritis	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026