Investigating peripheral visual sensitivity in people with glaucoma and normally-sighted individuals Eye Diseases Glaucoma
Conditions
Interventions
1. Eligibility screening tests:
1.1. Questions about eye and general health history, family history, and current medications
1.2. Measurement of vision on a standard eye chart
1.3. Measurement of eye
Sponsors
Cardiff University
Eligibility
Sex/Gender
All
Age
40 Years to 120 Years
Inclusion criteria
Inclusion criteria: Patients with glaucoma: 1. Diagnosis of Primary Open Angle Glaucoma (POAG) or Normal Tension Glaucoma (NTG) by the hospital eye service 2. Visual field defect consistent with glaucomatous optic nerve appearance. 3. Stable IOP <21 mmHg 4. Refractive error < ±6.00DS and <3.50DC 5. Visual acuity of 6/9 (+0.3 logMAR) or better in the test eye, in the absence of significant corneal or media opacities 6. Age over 40 years Normally-sighted individuals: 1. No clinical diagnosis of glaucoma or other retinal disease 2. Full visual field 3. Healthy optic disc 4. No family history of glaucoma (first-degree) 5. Refractive error <±6.00DS and <3.50DC 6. Visual acuity of 6/9 (+0.3 logMAR) or better in the test eye, in the absence of significant corneal or media opacities 7. Age over 40 years
Exclusion criteria
Exclusion criteria: 1. Any systemic disease and/or medication which is likely to affect visual performance (e.g. diabetes, thyroid disease) 2. Any ocular disease and/or medication that may affect visual performance (apart from glaucoma) 3. Any previous ocular surgery which may degrade visual performance (e.g. corneal graft, photodynamic therapy) 4. Inability to steadily fixate during the test (e.g. individuals who have nystagmus or macular degeneration)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in visual sensitivity between patients and normally-sighted individuals is measured at months 11, 22, and 39 | — |
Secondary
| Measure | Time frame |
|---|---|
| Variance of visual sensitivity in patients and normally-sighted individuals is measured at months 11, 22, and 39 | — |
Countries
England, Northern Ireland, United Kingdom, Wales
Contacts
Public ContactBecky Vangasse
Outcome results
None listed