Neutrophil Gelatinase Associated Lipocalin as a predictor of acute kidney injury post coronary angiogram

Neutrophil Gelatinase Associated Lipocalin (NGAL) as a predictor of acute kidney injury post coronary angiogram: a cohort observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN88709771

Enrollment

300

Registered

2012-03-13

Start date

2011-10-15

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Disease Urological and Genital Diseases Chronic nephritic syndrome

Interventions

Samples for serum and urine NGAL, serum cystatin C and serum creatinine will be collected directly pre- and post-contrast angiogram, and at 2, 4, 6, 24 and 48 hr time-points to allow time course analy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age > 18 years 2. Presenting for angiogram with known chronic kidney disease (CKD) [glomerular filtration rate (GFR) < 60mls/min]

Exclusion criteria

Exclusion criteria: 1. Myocardial infarction (MI) or acute coronary syndrome within previous 6 weeks 2. Hospitalisation within previous 6 weeks 3. Decompensated heart failure 4. Inability to give informed consent

Design outcomes

Primary

Measure	Time frame
Post procedure biomarker elevation diagnostic for acute kidney injury	—

Secondary

Measure	Time frame
Major cardiac adverse events (MACE) at 30 days and one year: 1. Myocardial infarction 2. Stroke 3. Heart failure hospitalisation 4. Death	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026