The prevention of malaria and anaemia in infants through iron supplementation and intermittent malaria treatment administered through the Expanded Programme on Immunization (EPI) Scheme (Tanzania)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN88523834

Enrollment

680

Registered

2006-02-01

Start date

1998-06-26

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Infections and Infestations Malaria

Interventions

All children receive oral daily iron syrup at a dosage of 2 mg/kg/day and will be randomly allocated to receive either intermittent malaria treatment (sulfadoxine-pyrimethamine) or a placebo at DPT2,

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All children who attend the Mother and Child Health (MCH) clinic for their second Diphtheria, Pertussis, Tetanus (DPT) and polio immunisations and who are permanent residents in the study area of Ifakara town.

Exclusion criteria

Exclusion criteria: Infants who are not permanent residents in Ifakara.

Design outcomes

Primary

Measure	Time frame
Incidence of clinical malaria and severe anaemia episodes in each group by 12 months of age.	—

Secondary

Measure	Time frame
1. Incidence of clinical malaria and severe anaemia episodes up to 18 months of age 2. Incidence of clinical malaria and severe anaemia from 10 to 18 months of age 3. Prevalence of malaria parasitaemia at 12 and 18 months of age 4. Prevalence of severe and moderate anaemia at 12 and 18 months of age 5. Total number of admissions and outpatient attendances	—

Countries

Tanzania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026