The role of autonomic responses to cardiopulmonary exercise testing in predicting surgical outcome in non-cardiac surgical patients

Conditions

Topic: Generic Health Relevance and Cross Cutting Themes

Gareth L. Ackland, Tom Abbott, Gary Minto, Martin R. Clark, Thomas Owen et al. (12 authors)

PLoS ONE2019-08-2121 citations

10.1371/journal.pone.0221277

Arterial pulse pressure and postoperative morbidity in high-risk surgical patients.

Ackland GL, Abbott TEF, Pearse RM, Karmali SN, Whittle J, Minto G, POM-HR Study Investigators.

2017-11-2110 citations

10.1016/j.bja.2017.11.009

Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients.

Abbott TEF, Minto G, Lee AM, Pearse RM, Ackland GL, POM-HR, POMO-O and OPTIMISE study groups.

2017-07-0125 citations

10.1093/bja/aex164

Interventions

No interventions, Observational

Follow Up Length: 0 month(s)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All surgical patients referred for cardiopulmonary exercise testing preoperatively undergoing major non-cardiac surgery 2. Aged 18-95 years

Exclusion criteria

Exclusion criteria: 1. History of exercise-induced angioedema 2. Pregnancy 3. Any contraindication to cardiopulmonary exercise testing (as outlined by American Association of Anaesthesia)

Design outcomes

Primary

Measure	Time frame
Post-operative morbidity survey; Timepoint(s): Preop, postop days 3, 7, 14	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed