Neonatal respiratory distress syndrome Neonatal Diseases
Conditions
Interventions
Preterm neonates stabilized according to the local NICU protocol and managed with any kind of respiratory support are enrolled within 120 minutes of birth when important prenatal variables were record
Sponsors
University of Naples Federico II
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Premature neonates with respiratory distress syndrome (RDS) 2. Born between 25- 33 weeks of gestational age calculated from the first day of the last menstrual period 3. Studied before their first surfactant dose
Exclusion criteria
Exclusion criteria: 1. Lack of parental consent 2. Major congenital malformations 3. Surfactant administration before lung ultrasound
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early LUS performance as a predictor of the second surfactant dose administration by a masked attending physician. LUS is performed in the first 2 hours of life using the Brat score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Main respiratory outcomes in relation to the need for a second surfactant dose, measured by evaluating oxygen indices and the respiratory technique used at stabilization. Bronchopulmonary dysplasia (according to the Jensen definition) and the number of deaths will be registered at discharge. | — |
Countries
Italy
Contacts
Public ContactFrancesco Raimondi
Outcome results
None listed