Topic: Cardiovascular, Generic Health Relevance and Cross Cutting Themes
Conditions
Interventions
Optimisation of fluid balance using SV targetted boluses of intravenous gelofusine 250 ml over 5 minutes compared to a cohort group having their fluid balance according to best usual practise (i.e., a
Sponsors
Nottingham University Hospitals NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients listed for surgical repair of fracture neck of femur under spinal anaesthesia 2. Aged greater than 60 years, either sex
Exclusion criteria
Exclusion criteria: 1. Planned general anaesthetic 2. Severe valvular heart disease previously shown on echocardiography (reduces reliability of monitor measurements) 3. Taking lithium (interferes with calibration of monitor) 4. Multiple injuries requiring operative management 5. Revision surgery or total hip arthroplasty for fractured neck of femur (a different patient/surgical population
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate if using a LiDCO machine (a minimally invasive device that measures how well the heart is pumping blood around the body) affects the time spent in hospital. Determined by the patients length of stay. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To use the LiDCO machine to characterise any changes in blood pressure and the amount of blood pumped 2. To investigate if using a LiDCO machine in patients undergoing hip fracture surgery with a spinal anaesthetic 3. To characterise the changes in the way the heart and blood vessels work after a spinal anaesthetic Outcome measures are determined by the patients length of stay. Mortality with be compared at 30, 60 and 90 days. | — |
Countries
United Kingdom
Outcome results
None listed