SALT STUDY: Effect of varying sodium intake and activity on plasma concentrations of N-Terminal BNP in normal subjects and patients with prior Q-wave myocardial infarction (MI)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN88264942

Enrollment

Registered

2005-09-30

Start date

2005-02-09

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sodium intake Nutritional, Metabolic, Endocrine Nutrition

Interventions

The results of this trial will be used to inform clinical decision making based on NT_BNP results. Other areas involved: Cardiology, Nuclear Medicine Department. The study is an open-label, randomise

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 30 normal subjects over 60 years old 2. 30 mobile patients over 60 years old who have had a Q-wave MI and left ventricular ejection fraction (LVEF) less than 45% Resources/Patient: 1. Electrocardiogram (ECG) 2. Echocardiography 3. Treadmill exercise with VO2 measurement for each patient

Exclusion criteria

Exclusion criteria: 1. No angina 2. No heart failure 3. Not receiving diuretics 4. No renal impairment

Design outcomes

Primary

Measure	Time frame
Brain Natriuretic Peptides (BNP)	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026