Effect of neuromodulation technique (tDCS) in reducing the craving and dependence in alcohol dependence

Comparative study of effect of tDCS (Trans cranial direct current stimulation) vs sham tDCS on reducing the craving and severity of dependence among patients of alcohol dependence syndrome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN88255964

Enrollment

Registered

2025-09-12

Start date

2024-03-10

Completion date

Unknown

Last updated

2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reducing the severity and dependence on alcohol in alcohol use disorder. Mental and Behavioural Disorders

Interventions

Participants were randomly allocated to one of two groups: Group A (active tDCS) or Group B(Sham tDCS) using a computer-generated random number sequence. Masking was done using the built-in sham proto

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 60 years (both genders) 2. A diagnosis of Alcohol Dependence Syndrome according to ICD-10 DCR criteria 14 3. Admission to the psychiatry ward

Exclusion criteria

Exclusion criteria: 1. Co-morbid substance use disorders (excluding nicotine). 2. Co-morbid psychiatric disorders 3. Uncontrolled or serious medical or surgical illnesses 4. Use of anti-craving or psychotropic medications (except benzodiazepines for withdrawal management) within the past month

Design outcomes

Primary

Measure	Time frame
Change in craving as measured using the Penn Alcohol Craving Scale (PACS) at baseline and after 10 sessions of tDCS at day 6	—

Secondary

Measure	Time frame
The role of severity as a mediator for the changes in cravings measured using the Severity of Alcohol Dependence Questionnaire (SADQ) at baseline and after 10 sessions of tDCS at day 6	—

Countries

India

Contacts

Public ContactShobit Garg

shobit.garg@gmail.com+91 8958534261

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026