Treatment of permanent front teeth affected by hypomineralisation (white and yellow spots)

Management of permanent incisor affected by hypomineralisation using resin infiltration

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN88218639

Enrollment

Registered

2022-05-04

Start date

2022-02-20

Completion date

Unknown

Last updated

2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molar incisor hypomineralisation Oral Health

Interventions

Participants are randomly allocated to either group A and group B using a random table. Group A is treated with Icon Etch for several cycles until a positive ethanol test is reached, not to exceed 3 c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children who have permanent incisor with opacities 2. Aged 6 to 16 years

Exclusion criteria

Exclusion criteria: 1. Children with signs of fluorosis, tetracycline staining, amelogenesis imperfecta, or generalized enamel hypoplasia 2. Undergoing orthodontic treatment 3. Opacities confined to the incisors only 4. Absence of parental consent to participate

Design outcomes

Primary

Measure	Time frame
1. Full or partial positive spot coverage measured using a coverage scale immediately after treatment 2. Parent's satisfaction measured using a Likert scale immediately after treatment	—

Secondary

Measure	Time frame
Lesion color measured using the easyshade Compact device before and immediately after treatment and after 3 months	—

Countries

Syria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026