Neurorehabilitation of chronic stroke patients Nervous System Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Post-stroke volunteers aged 18 - 80 years with normal or corrected to normal vision (e.g. normal vision by using glasses) 2. 6 months - 2 years post-stroke since first episode of stroke 3. Able to follow two-part spoken or written commands 4. Have movement disability in at least one of their hands due to stroke 5. Able to get in and out of a low seat unassisted 6. Prepared to remove all body piercings
Exclusion criteria
Exclusion criteria: 1. Known to have a progressive neurological condition 2. Have metal or active implants in their body (excluding dental fillings or crowns) 3. Known to suffer from claustrophobia 4. Pregnant or breast feeding 5. Gross cognitive impairment or disorientation, evidenced by a Hodgkinson mini-mental test score (HMMS) (Hodgkinson, 1972) of less than 21/30
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Functional recovery measured using the Action Research Arm Test (ARAT) and grip strength on a weekly basis during the trial period 2. Functional connectivity among activated brain regions will be computed using activation related MEG/EEG-EMG data on a weekly basis during the trial period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Participants’ mood, motivation, and fatigue levels will be continuously monitored during sessions using appropriate methods including visual analog scales 2. Mood will be assessed weekly, using the Centre for Epidemiologic Studies-Depression Scale | — |
Countries
Ireland, Northern Ireland, United Kingdom