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Cost-effectiveness analysis of 2-octyl cyanoacrylate tissue adhesive and suture for closure of simple lacerations: Randomised Controlled Trial

Cost-effectiveness analysis of 2-octyl cyanoacrylate tissue adhesive and suture for closure of simple lacerations: Randomised Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN87805481
Enrollment
120
Registered
2007-08-24
Start date
2005-10-01
Completion date
Unknown
Last updated
2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Simple laceration wound repair Injury, Occupational Diseases, Poisoning Simple laceration

Interventions

Patients were randomly allocated to one of the two treatment groups using a computer generated randomised number system. One group received suturing materials (4-0 to 6-0 monofilament suture, Tyco Hea

Sponsors

The Health and Health Services Research Fund (HHSRF) (Hong Kong)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients aged greater than or equal to 18 years presenting to the ED between 9 am to 5 pm, Monday to Friday, with traumatic lacerations or incised wounds were eligible for the study.

Exclusion criteria

Exclusion criteria: To standardise the recruited cases for comparison, wounds with the following features were excluded: 1. Wound length greater than 8 cm 2. Deep wounds with muscle, tendon, bone, joint or neurovascular structure involvement 3. Scalp wounds 4. Vermilion border involvement at lip 5. Stellate lacerations 6. Stab wounds to the trunk or neck 7. Heavily contaminated or infected wounds 8. Animal or human bite 9. Wounds which required debridement of devitalised tissue 10. Wounds in which haemostasis could not be achieved within 20 minutes by direct pressure 11. Wounds greater than 12 hours old 12. We also excluded patients with a history of keloid formation or with physical or cognitive impairment making the use of visual analogue scales inaccurate

Design outcomes

Primary

MeasureTime frame
The primary outcome measure was the Cosmetic Visual Analogue Scale (CVAS) score, measured at baseline, day 14, 30 and 90.

Secondary

MeasureTime frame
Secondary outcome measures included: 1. Visual Analogue Scale (VAS) score, measured at baseline, day 14, 30 and 90 2. Wound Evaluation Scale (WES) score, measured at day 14 3. Total time spent in each closure method 4. The overall patients' satisfaction, measured at day 30 5. The total costs required per patient in each method

Countries

Hong Kong

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026