A randomised clinical trial of cardiopulmonary resuscitation (CPR) prior to defibrillation for the treatment of out-of-hospital ventricular fibrillation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN87778564

Enrollment

256

Registered

2003-03-27

Start date

2000-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest Circulatory System Cardiac arrest

Interventions

Patients meeting the above criteria were randomised to receive either defibrillation as soon as possible in line with existing treatment guidelines (Control arm) or 90 seconds of oxygen supplemented C

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients older than 16 years suffering cardiac arrest outside of hospital in which the underlying cardiac rhythm was ventricular fibrillation upon arrival of Ambulance Paramedics

Exclusion criteria

Exclusion criteria: 1. Patients with known allergies to Fentanyl 2. Patients unable to receive intranasal fentanyl due to facial and / or nasal trauma 3. Patients who are pregnant

Design outcomes

Primary

Measure	Time frame
Survival to hospital discharge.	—

Secondary

Measure	Time frame
1. Return of spontaneous circulation. 2. Survival at one year	—

Countries

Australia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026