Parkinson's disease Nervous System Diseases
Conditions
Interventions
Each participant is invited to one visit only. Participants will be asked to fast overnight for 6-8 hours and to arrive at the University of Auckland in the morning time at a pre-arranged time. They a
Sponsors
University of Auckland
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged =18 years 2. A diagnosis of idiopathic PD, diagnosed by a neurologist 3. Available to attend the Liggins Institute at the Grafton campus of the University of Auckland 4. The mental capacity to consent to participate in this research
Exclusion criteria
Exclusion criteria: 1. People with medical, cognitive, or psychosocial issues that would preclude compliance with the protocol, confirmed by a principal investigator or neurologist 2. Co-enrolment in another study or trial that, in the opinion of the principal investigators, would interfere with adherence to study requirements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Recruitment rate, number of eligible participants, and length of time taken to recruit 10 participants measured using standard questions by 6 months. 2. Feasibility and acceptability of the measurement of gastric symptoms using the body surface gastric mapping device in 10 participants using existing questions by 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Participant acceptability of completion of questionnaires listed here, assessed using standard questions at baseline 2. Quality of life measured using Parkinson’s Disease Questionnaire 8 at baseline 3. Motor and non-motor symptoms measured using the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS UPDRS) at baseline 4. Non-motor symptoms measured using the Movement Disorder Society Non-Motor Symptom Rating Scale (MDS NMS) at baseline 5. Gastrointestinal symptoms measured using the Gastrointestinal Symptom Rating Scale at baseline 6. Gastrointestinal symptoms measured using the MDS Gastrointestinal Dysfunction Scale for Parkinson’s Disease at baseline 7. Dietary intake measured using intake24 at baseline 8. Gastric electrophysiological and symptom response to a standard test meal in Parkinson’s up to 4 hours post consumption of the test meal compared with a matched control group | — |
Countries
New Zealand
Outcome results
None listed