Haematology and vascular surgery Surgery
Conditions
Interventions
Enrolled patients will have additional blood tests during their surgery - withdrawal of additional 2.7 ml of blood with each monitoring episode. Up to an additional 16 ml of blood may be sampled durin
Sponsors
Royal Free London NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult patients able to give informed consent and undergoing elective major complex vascular surgery in which heparin anticoagulation and monitoring is indicated
Exclusion criteria
Exclusion criteria: 1. <18 years old 2. Unable to consent 3. History of heparin allergy 4. Already taking part in research study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlate ACT and anti-Xa levels during aortic surgery - measured at baseline and up to six time points during surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood loss and bleeding will be measured during theatre 2. Clotting complications will be monitored during theatre and first week postoperatively | — |
Countries
United Kingdom
Outcome results
None listed