Patients with recurrent herpes labialis Infections and Infestations
Conditions
Interventions
Current interventions as of 14/01/2025:
This is a randomized controlled clinical study in which the patient sample will be divided into three equal groups according to the method of treatment used, an
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Good general health 2. 18 years of age or older 3. Recurrent herpes labialis in the vesicular stage 4. Other treatments for the present lesion
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating 2. Patients who took antiviral drugs during the four weeks preceding treatment 3. Patients who took anti-inflammatory drugs or antibiotics during the two weeks preceding treatment 4. Diabetes 5. Patients with skin injuries that affect the course of healing or interfere with the results of the study 6. Patients who have allergic reactions to the medications used 7. Immunocompromised patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures are assessed at baseline (T0: Before taking any action in the first session) and at the following time points: 1. Pain measured using a visual analogue scale (VAS) 2. Healing speed measured using study records of the day the crust of the lesion falls off spontaneously T1: After applying the laser (activated or placebo) in the first session T2: The second session (after 48 hours) before applying the laser (activated or placebo) T3: The second session after applying the laser (activated or placebo) T4: Third session after 7 days. The day when the pain has completely disappeared is also recorded. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain measured using a VAS on day 7 | — |
Countries
Syria
Outcome results
None listed