Mild Cognitive Impairment (MCI) Mental and Behavioural Disorders
Conditions
Interventions
This is a phase II randomized, double-blind clinical trial with a 3-month follow-up period. The study aims to enroll 62 participants diagnosed with Mild Cognitive Impairment (MCI) aged over 60 years,
Sponsors
Universidad del Desarrollo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age equal to or greater than 60 years 2. Presence of Mild Cognitive Impairment, according to the diagnostic criteria established in Petersen et al. (2014) 3. Have six or more years of complete schooling (presence of reading and writing)
Exclusion criteria
Exclusion criteria: 1. The previous diagnosis of other neurodegenerative diseases 2. Attending another cognitive training program 3. History of Epilepsy or current presence of epileptic seizures 4. Presence of psychiatric diseases 5. Presence of a relevant depressive picture (GDS >=2) 6. History of important neurological alterations such as the history of stroke, transient ischemic attack, cranial brain trauma 7. Important alterations of communication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prefrontal theta oscillation activity is measured using electrophysiological changes underlying the working memory process at baseline, 13 and 20 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Working Memory Index is measured using WAIS-IV Digit Retention subtest at baseline, 13 and 20 weeks 2. Working memory and the capacity for cognitive flexibility are measured using Trail Making Test B (TMT-B) at baseline, 13 and 20 weeks | — |
Countries
Chile
Outcome results
None listed