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Community evaluation of three-dimensional window double screens in reducing malaria transmission

A cluster-randomized controlled Phase III evaluation of 3D window double screens (3D-WDS) in reducing malaria transmission when combined with pyrethroid-treated long-lasting insecticidal net in north-eastern Tanzania

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN87169034
Enrollment
526
Registered
2022-10-28
Start date
2019-10-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Infections and Infestations Unspecified malaria

Interventions

20 clusters from 17 villages across Muheza district in the northeast of Tanzania were profiled based on the malaria point prevalence, malaria vector densities and level of insecticide resistance. A st

Sponsors

University of Helsinki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Traditional Tanzanian village house with at least a single window or outlet which can accommodate the 3D-WDS and at least a single sleeping space 2. House made for long-term residential purposes (at least for the duration of the study) 3. At least one child aged 6 months - 14 years sleeping inside the house 4. Consent to 4.1. Install 3D-WDS in the house (intervention clusters only) 4.2. Use insecticide-treated nets (both intervention and control clusters) for a period of 12 months after the installation 4.3. Malaria screening for at least one child of the household

Exclusion criteria

Exclusion criteria: 1. Community houses with fixed window panels, shutters, or well-constructed aluminium panels with glass windows 2. Houses without a sleeping space i.e., made for the purpose of cooking and dining or cattle shed 3. Buildings that are temporarily constructed or made with the purpose to serve as a community hall, recreational centre, mosque or church 4. Households with no children aged 6 months to 14 years 5. Children without informed consent 6. Children with health conditions that require frequent hospital or health centre visits

Design outcomes

Primary

MeasureTime frame
Malaria prevalence measured using a rapid diagnostic test and thick blood smear at baseline, 10, 20, 30, 40 and 50 weeks

Secondary

MeasureTime frame
Current secondary outcome measures as of 11/09/2024: 1. Anemia prevalence determined by measuring hemoglobin level using the Hemocue device at baseline, 10, 20, 30, 40 and 50 weeks 2. Body temperature measured using an infrared thermometer at baseline, 10, 20, 30, 40 and 50 weeks 3. Bio-metrics (height, weight and MUAC) measured using a measuring tape and weight scale at baseline, 10, 20, 30, 40 and 50 weeks 4. Indoor mosquito density measured using CDC-light traps at baseline, 10, 20, 30, 40 and 50 weeks 5. Entomological inoculation rate measured using CDC-light traps and RT-PCR at baseline, 10, 20, 30, 40 and 50 weeks 6. Acceptability of intervention measured using focus group discussions and interviews starting from week 50 over 3 weeks Previous secondary outcome measures: 1. Anemia prevalence is determined by measuring hemoglobin level using the Hemocue device at baseline, 10, 20, 30, 40 and 50 weeks 2. Body temperature is measured using an infrared thermometer at baseline, 10, 20, 30, 40 and 50 weeks 3. Bio-metrics (height, weight and MUAC) are measured using a measuring tape and weight scale at baseline, 10, 20, 30, 40 and 50 weeks 4. Indoor mosquito density is measured using CDC-light traps at baseline, 10, 20, 30, 40 and 50 weeks 5. Acceptability of intervention is measured using focus group discussions and interviews starting from week 50 over 3 weeks

Countries

Tanzania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 5, 2026