Aging and skeletal muscle loss Musculoskeletal Diseases
Conditions
Interventions
Participants self-select into an experimental exercise or control non-exercising group. Physical function, cognitive performance, and balance data are collected every 14 weeks, and muscle and bone mas
Sponsors
University of Houston - Clear Lake
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. At least 40 years of age 2. Have the ability to perform lower- and upper-body exercises 3. Commit to exercise 2-3 times per week (experimental group only) 4. Free from overt neurologic disease or injury
Exclusion criteria
Exclusion criteria: Overt neurologic disease or inability to ambulate safely without assistance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle mass and bone mineral density measured with dual x-ray absorptiometry every 42 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Force and power output measured with force plates during the sit-to-stand test every 14 weeks 2. Total time to complete the Timed-up-and-go test measured every 14 weeks 3. Time to complete and number of steps measured in the forward 10-meter walk test performed every 14 weeks 4. Time to complete and number of steps measured in the backward 10-meter walk test performed every 14 weeks 5. Sway magnitude measured with a computerized dynamic posturography device during a sensory organization text every 14 weeks 6. Total distance walked during the 6-minute walk test completed every 14 weeks 7. Cognitive function measured with Bell’s test, mini-cognitive assessment, Trails A&B, the Digit-Symbol, and Navigation measured every 14 weeks 8. Daily workout volume-load measured using the weight lifted multiplied by the sets and repetitions 9. The number of falls documented monthly 10. Blood pressure measured monthly with a sphygmomanometer 11. Body weight measured monthly with a digital scale | — |
Countries
United States of America
Outcome results
None listed