Skip to content

Cognitive behaviour therapy for co-morbid obsessive compulsive disorder in autism spectrum disorder

Is cognitive behaviour therapy an effective treatment for obsessive compulsive disorder in people with high functioning autism spectrum disorders?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN87114880
Enrollment
40
Registered
2008-04-21
Start date
2007-03-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disabling obsessions and compulsions in autism spectrum disorders Mental and Behavioural Disorders Obsessive-compulsive disorder

Interventions

Intervention treatment: CBT for obsessive compulsive disorder (OCD) Control treatment: Stress management Both treatments contain a significant psycho-educational component about anxiety. The CBT fo

Sponsors

Kings College London, Institute of Psychiatry (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male and female, aged 14 years or older to a maximum of 65 years old 2. Verbal intelligence quotient (IQ) greater than 70 3. Diagnoses of ASD and co-morbid OCD

Exclusion criteria

Exclusion criteria: 1. Current acute symptoms of psychosis 2. Uncontrolled seizure disorder or substance misuse disorder

Design outcomes

Primary

MeasureTime frame
The following will be assessed at baseline (pre-treatment), end of treatment, 1, 3 and 6 months follow-up: 1. The Dimensional Yale Brown Obsessive Compulsive Scale (D-YBOCS) 2. The Obsessive Compulsive Inventory Revised (OCI-R) or Childrens Obsessive Compulsive Inventory (CH-OCI) 3. Beck Depression and Anxiety Scales or Spence Children's Anxiety Scale 4. Clinical Global Impressions Scale

Secondary

MeasureTime frame
The following will be assessed at baseline (pre-treatment), end of treatment, 1, 3 and 6 months follow-up: 1. Liebowitz Social Anxiety Scale 2. Family Accommodation Scale 3. Work/School and Social adjustment scale 4. Parental CH-OCI

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 24, 2026