A randomised study to compare the effectiveness of hyoscine hydrobromide (Hyoscine) and glycopyrronium (Robinul) in the management of noisy breathing/retained secretions in cancer patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN87058979

Enrollment

205

Registered

2003-09-12

Start date

2002-02-28

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer: Noisy breathing, retained secretions Cancer Malignant neoplasm without specification of site

Interventions

Randomised test intervention versus standardised intervention, non-blinded (Phase 3).

Eligibility

Inclusion criteria

Inclusion criteria: Total number of Royal Marsden Hospital patients 205

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. Provide an evidence base for common practice 2. Provide a means of obtaining consent for research in dying patients	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026