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Persistent digestive disorders and their association with bacterial, parasitic and viral pathogens in Dabou, south Côte d?Ivoire

Persistent digestive disorders and their association with bacterial, parasitic and viral pathogens in Dabou, south Côte d?Ivoire: an exploratory case-control study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN86951400
Enrollment
320
Registered
2013-10-02
Start date
2012-10-01
Completion date
Unknown
Last updated
2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent diarrhoea, gastrointestinal infection, bacteria, helminths, intestinal protozoa, viruses Infections and Infestations

Interventions

All non-pregnant participants who are diagnosed with soil-transmitted helminths and symptomatic participants who are diagnosed with intestinal protozoa will be offered free treatment:
pediatric dose: 5 mg/kg) No follow-up examinations were performed in our study, meaning that all examinations were carried out at baseline.

Sponsors

Institute of Tropical Medicine (Belgium)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Individuals aged above 12 months presenting with persistent diarrhoea (=3 stools per days for =14 days; symptomatic group) or without any gastrointestinal complaints in the 4 preceding weeks (asymptomatic control group) will be eligible to participate. 2. Participants from the City of Dabou and 11 surrounding villages will be invited to participate. 3. Written informed consent of all participating individuals will be obtained. If the individual is aged below 16 years, the written informed consent will be signed by the child?s parents or legal guardians; additionally, these young participants will assent orally.

Exclusion criteria

Exclusion criteria: 1. Individuals in need of immediate intensive care. 2. Individuals who are unable or unwilling to give written informed consent. 3. Individuals who do not meet the inclusion criteria for either study group, e.g. people with acute diarrhoea.

Design outcomes

Primary

MeasureTime frame
Infection status in relation to gastrointestinal complaints measured using a clinical questionnaire and battery of diagnostic tests employed on human stool samples.

Secondary

MeasureTime frame
Clinical symptomatology and related variables (specific symptoms, treatment prior to enrolment, age and sex), comparison of different diagnostic techniques measured using a clinical questionnaire and battery of diagnostic tests employed on human stool samples.

Countries

Cote d'Ivoire

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 15, 2026