Change of periodontal inflammatory indicators through a 4-week weight control intervention including caloric restriction and exercise training in young Koreans

Change of MMP-8, MMP-9, and IL-1beta in gingival crevicular fluid through a 4-week weight control intervention including caloric restriction and exercise training in young Koreans

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN86753073

Enrollment

Registered

2015-08-14

Start date

2011-06-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body mass index of >25 Nutritional, Metabolic, Endocrine

Interventions

The subjects stayed in the camp under surveillance for two hours of aerobic exercise, three hours of weight training, and a low salt-low fat diet (=1,300 kcal/day). They were not allowed to have any p

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Obese individuals (body mass index of >25) aged 20 to 29 and 13 camp trainers of the same age

Exclusion criteria

Exclusion criteria: 1. Systemic disease exclusive of obesity 2. Use of steroidal or non-steroidal anti-inflammatory drugs or antibiotics in the last three months or during the program 3. Use of mouthwash in the last three months or during the program 4. Need of dental or medical treatment during the program 5. Fewer than 24 teeth 6. Sites with probing periodontal pocket depth (PD) > 3.5 mm 7. Self-directed dropout during the course of the weight-control program

Design outcomes

Primary

Measure	Time frame
MMP-8, MMP-9, and IL-1beta in gingival crevicular fluid	—

Secondary

Measure	Time frame
Gingival index	—

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 4, 2026