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The effect of dairy fat on metabolic health

The effect of dairy fat on metabolic health - understanding the 'matrix' effect of cheese

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN86731958
Enrollment
240
Registered
2015-09-22
Start date
2015-09-01
Completion date
Unknown
Last updated
2023-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine

Interventions

Participants will be randomised into one of four groups, each receiving dairy fat in different forms: Group 1: To receive dairy fat in the form of regular fat cheese Gr

Sponsors

Food for Health Ireland
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy, on no medication 2. Not following a prescribed diet for any reason (weight loss, cholesterol etc) 3. Male or female, aged between 50-70 4. BMI >25 kg/m2

Exclusion criteria

Exclusion criteria: 1. Outside the specified age 2. BMI <25 kg/m2 3. Anyone who is currently taking prescribed medication for cholesterol-reduction purposes 4. Anyone following any specific diet to control or modify their cholesterol or weight

Design outcomes

Primary

MeasureTime frame
Fasting blood markers of metabolic health following 6 weeks daily consumption of dairy fat, in 3 different matrices. A subset of subjects (n=24) will give multiple blood samples (8 in total) over 5 hours. Analysis will be performed at all time points.

Secondary

MeasureTime frame
Postprandial blood-lipid and glucose following an oral lipid challenge in a subset of subjects.

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026