Patients with glucocorticoid-induced osteonecrosis of the femoral head Musculoskeletal Diseases
Conditions
Interventions
This is a non-interventional, biological specimen research study. It involves the use of hip joint tissues that are routinely removed and discarded during standard total hip arthroplasty surgery from
Sponsors
Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Experimental group: Patients with femoral head necrosis undergoing THA surgery in our hospital 2. Control group: Patients with femoral neck fracture or hip osteoarthritis undergoing THA surgery in our hospital 3. Willingness to participate in the study and provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with unclear diagnosis 2. Issues with sample quality:Biological samples with severe contamination or other problems during collection, transportation or preservation, which may affect the accuracy of experimental test results.Samples with insufficient quantity to meet the requirements of experimental detection, making them unsuitable for IHC assays. 3. Special populations and other conditions:Pregnant or lactating women. 4. Patients who have recently (within one month) used drugs that may affect experimental results. 5. Patients with severe systemic diseases such as heart, liver or kidney diseases, or those with mental illnesses, malignant tumors or other diseases that may affect research results or life expectancy.
Countries
China
Contacts
Public ContactYage Luo
Outcome results
None listed