Efficacy and Cost Effectiveness of Selective Single Embryo transfer

Efficacy and Cost Effectiveness of Selective Single Embryo transfer: a multi-centre randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN86466058

Enrollment

700

Registered

2006-01-16

Start date

2005-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility Pregnancy and Childbirth Infertility

Interventions

Single-embryo transfer or double-embryo transfer. Added 21/02/2007: Please note that this trial has been stopped due to poor recruitment and the fact that the clinical question is less relevant as ma

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women aged 37 years or less 2. Undergoing In Vitro Fertilisation (IVF) or Intracytoplasmic Sperm Injection (ICSI) 3. In the first or second cycle of treatment or with a previous IVF live birth 4. Four or more good quality embryos at the time of embryo transfer

Exclusion criteria

Exclusion criteria: 1. Pre-implantation genetic diagnosis 2. Assisted hatching 3. History of recurrent miscarriage (three or more) 4. Multiple IVF failure 5. Donor or recipient of gametes 6. Previous non-IVF live birth

Design outcomes

Primary

Measure	Time frame
Live birth per woman.	—

Secondary

Measure	Time frame
1. Pregnancy rate per woman 2. Multiple pregnancy rate 3. Obstetric and perinatal morbidity 4. Cost effectiveness and cost utility 5. Acceptability and satisfaction	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026